If you've spoken to a dermatologist, you've probably heard of spironolactone
PMC10056213 Subcutaneous injection osmolality, pH, and volume effects on pain and absorption
Reported Side Effects (Mild and Rare) Nausea Occasionally reported when injected near the stomach or when dosing is too high Headache Often from stacking with other peptides (e.g., GH secretagogues) Dizziness or lightheadedness Linked to vasodilation or nitric oxide regulation Injection site irritation Mild redness or swelling is possible with subcutaneous use These effects are usually short-lived and self-resolving , especially when using proper injection technique and sterile reconstitution practices
In summary, cyanocobalamin supplementation, even at small doses, has a marked impact on the above blood parameters for the average person with either low B12 intakes or mild B12 malabsorption, including for older people
Other contraindications and caution flags include Wilsons disease or another copper-handling disorder, pregnancy, recent surgery, and WADA-tested competition